About the Institute of Chemistry, SAS People at the Institute of Chemistry, SAS Research groups at the Institute of Chemistry, SAS Research at the Institute of Chemistry, SAS Products of the Institute of Chemistry, SAS






PhD study
  • Stability studies and synthesis of a potential inhibitors of human glycosyltransferases.
  • Supervisor: Marek Baráth, PhD

  • Modified glycan interfaces and their applications.
  • PhD student: Filip Květoň, MSc

  • Regulatory mechanisms of the mitochondrial phospholipid cardiolipin formation in the yeasts Saccharomyces cerevisiae
  • PhD student: Lucia Pokorná, MSc
    Supervisor: Peter Griač, PhD

  • Analysis of complex carbohydrates by biosensors.

  • Antimicrobial substances of honeybee larval jelly: the investigation of their contents in jellies in bee colonies and the efficiency against pathogens of bee brood.
  • PhD student: Maroš Laho, MSc

  • Synthesis, characterization and properties of potential inhibitors of glycosyltransferases.

  • Mass spectrometry of flavours and fragrances.

  • Characterization of new genes essential for correct meiotic segregation of chromosomes in yeast Schizosaccharamyces pombe.
  • PhD student: Ivana Mišová, MSc
    Supervisor: Peter Griač, PhD

  • Phospholipids and their influence on morphology and function of mitochondria.
  • Supervisor: Peter Griač, PhD

  • Multiparameter characterization of a new generation of immobilized biocatalysts.
  • Supervisor: Marek Bučko, PhD

  • Study of the glycosylation changes of proteins as potential biomarkers using biochips.

  • Chemoenzymatic synthesis of bioactive glycophenolics.
  • PhD student: Peter Kis, MSc

  • Synthetic glycoconjugates for various medicinal chemistry studies.
  • PhD student: Tomáš Klunda, MSc

  • Biopolymers of microalgae, structure and properties.
  • PhD student: Michal Halaj, MSc
    Supervisor: Peter Capek, PhD

  • Lipid droplets as multifunctional organelles of eukaryotic cells.
  • PhD student: Zsófia Csáky, MSc
    Supervisor: Ivan Hapala, PhD

  • Regulatory mechanisms of lipid homeostasis in the yeast Saccharomyces cerevisiae.
  • Supervisor: Peter Griač, PhD

  • Label-free electrochemical glycoprofiling of prostate cancer biomarkers.

  • Glyco-recognition by microarray and SPR biochips.

  • Enzymes required for plant hemicellulose utilization.

  • Cell mechanism of sterols.
  • PhD student: Marek Pápay, MSc

  • Preparation, characterization and applications of lectin devices in cancer diagnosis.

  • Synthetic potential of glycosidases.


  • 2016
  • Preparation and utilization of glycan biochips.

  • Application of nanotechnologies in preparation of lectin biosensors.

  • Inhibition of the cell wall formation in yeast.

  • Study of relation between structure and function of glycoconjugates in living systems.
  • Supervisor: Ján Mucha, PhD

    2015
  • Study of immunity responce induced by surface saccharides of microbial pathogens.

  • Investigation of biomolecular factors of the defense of honeybee colonies against microbial pathogens.

  • Expression and biochemical characterization of selected glycoenzymes.

  • Enzymatic acylations of saccharides.
  • PhD student: Andrej Chyba, MSc

  • Biochips and biosensors based on lectin biorecognition.

  • Regulatory mechanisms of lipid homeostasis in the yeast Saccharomyces cerevisiae.
  • PhD student: Peter Seč, MSc
    Supervisor: Peter Griač, PhD

  • Development of new high performance technique for the encapsulation of biocatalysts for production of aromas.
  • Supervisor: Marek Bučko, PhD

    2014
  • The role of apiculate microflora in vineyard ecosystem and winemaking.

  • Expression and biochemical characterization of selected bioenergetic enzymes.
  • Supervisor: Jozef Nahalka, PhD

  • Vibrio cholerae antigens. Preparation and immunogenicity of glycoconjugates.

  • Preparation of nanostructured interfaces and their use in biorecognition.

  • Structure-function relationship of plant transglycosylases.

  • Immunobiological characteristiques of polysaccharidic antigens of pathogenic Candida spp.

  • 2013
  • Production of antimicrobial peptides in honeybee colonies.

  • Úloha kvasinkového fosfatidylinozitol transferového proteínu a jeho homológov vo fyziológii eaukaryotickej bunky.
  • Supervisor: Peter Griač, PhD

  • Molekulárne mechanizmy kontroly biogenézy neutrálnych lipidov u kvasiniek.
  • Supervisor: Ivan Hapala, PhD

  • Construction and application of enzymatic and microbial biofuel cells (biobaterries) using nanotechnological tools.
  • PhD student: Jaroslav Filip, PhD

  • Diversity of yeasts inhibiting the plant material with emphasis on their characteristics and activity.

  • Genetically engineered microorganisms as whole-cell catalysts for enantioselective biooxidations by novel immobilization biotechnologies.

  • Role of the lipid transfer proteins in metabolism of eukaryotic cell.
  • Supervisor: Peter Griač, PhD

    2012
  • Study of the affinity interactions of biomolecules on the solid support by quartz crystal microbalance.

  • 2011
  • NMR study of metabolism of bacteria isolated from clouds water: their role in chemistry of the atmosphere.
  • Supervisor: Anne Marie Delort, PhD (University Blaise Pascal, Clermont Ferrand, France)

  • Molecular modeling of catalytic mechanism of glycosyltransferases and design of their inhibitors.
  • PhD student: Michal Raab, PhD

  • Biological and immunological characterization of antigen dominant mannoproteins of pathogen yeasts Candida; their utilization for preparation of subcellular vaccines.

  • Newly emerging pathogens - vibrios. Study of virulence and possible active immunomodulative prevention.
  • PhD student: Jana Korcová, PhD

    2010
  • Molecular modeling of the transition state structure of catalytic reactions.

  • Microbial esterases of wooddestroying fungi Phanerochaete chrysosporium.

  • Regulation of capsule formation in the yeast Cryptococcus.

  • 2009
  • Novel assay methods for transglycosylases.
  • PhD student: Ondřej Kosík, PhD

  • Preparation and immunological properties of mannan-protein conjugates of potential pathogenic Candida and Malassezia species.
  • Supervisor: Eva Machová, PhD

  • New flow biosensor systems with amperometric and calorimetric detection for fermentation and biotransformation monitoring.

  • Structure - function study of Arabidopsis thaliana core α 1,3-fucosyltransferase (FucTA).
  • PhD student: Peter Both, PhD
    Supervisor: Ján Mucha, PhD

  • Isolation and characterization of plant transglycosylases.

  • Synthesis of glycofuranosyl and glycopyranosyl C-nucleosides and their analogs.
  • PhD student: Michal Vojtech, PhD

  • Preparation and structural characterization of bioactive and other functional polysaccharides from economically important agricultural plants.

  • 2008
  • Immobilized biosystems: Potential and limitations of encapsulation of biocatalysts in polymer microcapsules.
  • PhD student: Marek Bučko, PhD

  • The role of transglutaminase in biosynthesis fungal cell walls.

  • Synthesis and characterization of neoglycoconjugates based on LPS of Vibrio cholerae 01.

  • Hyaluronic acid derivatives with biological properties.

  • 2007
  • Regulation of xylogenesis in vitro - effect of GGMOs on tracheary elements differentiation.

  • Microbial esterases of wooddestroying fungi Schizophylum commune.

  • The influence of chemical and physical factors on the yeast microflora in winery large production.

  • Reaction mechanism of glycosyltransferases.

  • Identification and some aspects of expression of larval nutrition antimicrobial peptide - royalisine in various colonies of honeybees Apis mellifera L.

  • Utilization of MALDI and ESI-MS techniques in the study of biomolecules.

  • 2006
  • Preparation, chemical and immunological characterization of glycoconjugates based on polysaccharidic surface antigens from the yeasts of Candida genus as potential vaccines.

  • Conidiation of Trichoderma fungi and its utilization in the culture plants protection.

  • Preparation of mimetics of lipide A.

  • Assay methods and isolation of xyloglucan endotransglycosylase (XET) isoforms from nasturtium (Tropaeolum majus) seeds.

  • 2005
  • Xylanolytic system of Schizophyllum communae.

  • Synthesis of anhydronitroalditol-based C-glycosylating agents.

  • Synthesis and characterization of aminoderivatives of saccharides structurally related to mannojirimycin.

  • Use of lignin in polymer blends.

  • 2003
  • Mechanism of reaction catalyzed by xyloglucan endotransglycosylase (XET).

  • Biophysical study of hyaluronan structure and pahtological processes in cartilage and brain using nuclear magnetic resonance.

  • Mrjp gene family of honeybee (Apis mellifera L.): computer analysis of putative mrjp promoters and genomic structure of mrjp1 gene coding for the most abundant protein of royal jelly.

  • Synthesis of bioactive proteins of larval nutrition of honey bees by heterologous expression.

  • 2002
  • Synthesis of glycoproteins. Preparation, characterization and their interaction with concanavalin A.

  • Isolation, characterization and function of lectin from Pinus nigra ARN.

  • Isolation and characterization of biologically active proteins and antimicrobial peptides of honeybee royal jelly.

  • 2001
  • Synthesis and properties of model compounds for ester type of lignin-carbohydrate linkage.
  • Supervisor: Dušan Joniak, PhD

  • Photoinduced conidiation in the fungus Trichoderma viride.

  • Plant β-mannans and their enzymatic degradation.

  • Biosynthesis of galactosylated glycoproteins in the yeast Cryptococcus laurentii.

  • 1999
  • Annulated derivatives of purine-2,6-diones.
  • Supervisor: Alfonz Rybár, PhD

  • Synthesis of C-glycosyl analogues of biologically significant saccharides.

  • Biotechnological use of plant cell biomass for production of secondary metabolites.

  • Mutual isomerization of 2-ketoses and 2-C-(hydroxymethyl)aldoses catalyzed by molybdic acid.

  • Isolation and biochemical characterization of a GTP-ase-activating protein specific for members of Ypt/Rab family of small GTP-ases.

  • 1998
  • Chemical ionization mass spectrometry of saccharides.

  • Characterization of immobilized biocatalysts using flow microcalorimetry.

  • β-Mannanolytic system of Aureobasidium pullulans.

  • Institute of Chemistry
    Slovak Academy of Sciences
    webmaster@chem.sk
    2017