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Research Interests
Synthesis and characterization of neoglycoconjugates based on LPS from Vibrio cholerae 01. Derivatization of carboxyl groups of LPS with various linkers and subsequent conjugation to proteins via these new functionalities.
Publications
Chemical conjugation of biomacromolecules: A mini-review.
Farkas, P., Bystricky, S. Chemical Papers, 64, in press. DOI: 10.2478/s11696-010-0057-z.(2010)
Immunomodulatine properties of conjugates composed of detoxified lipopolysaccharide and capsular
polysaccharide of Vibrio cholerae O135 bound to BSA-protein carrier.
Korcová J., Machová E., Farkaš P., Bystrický S. Biologia 65/5, 1- , 2010
Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group.
Kronek, J., Luston, J., Kronekova, Z., et al. Journal of Materials Science-Materials in Medicine 21, 879-886, 2010
Preparation of synthetic polyoxazoline based carrier and Vibrio cholerae O-specific polysaccharide
conjugate vaccine.
Farkas, P., Korcova, J., Kronek, J., et al. European Journal of Medicinal Chemistry 45, 795-799, 2010
Hydrolysis of the terminal dimethylacetal moiety on the spacers bound to carboxy groups containing glucans.
Farkas, P., Bystricky, S. Carbohydrate Polymers 74, 133-136, 2008
Efficient activation of carboxyl polysaccharides for the preparation of conjugates.
Farkas, P., Bystricky, S. Carbohydrate Polymers 68, 187-190, 2007 |